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A method to prevent disseminated candidiasis by targeting and inhibiting CBL-b, a ligase that prevents the immune system from functioning properly.
Small molecules for targeted treatment of triple negative breast cancer and other aggressive phenotypes.
Novel bacteria, specially formatted, could be utilized as a microbial therapeutic for diminishing the risk of arteriosclerosis and subsequent heart disease.
A method for providing guidance and feedback during gesture-driven data exploration
Middleware layer that queries in the context of sampling and improves efficiency of common statistical analyses.
A database management systems that can execute joins with rapid response times.
Methionine salvaging is a totally anaerobic (oxygen deficient) process by which large amounts of ethylene are made as a result of manipulating bacterial metabolism in select microorganisms.
A program to transform time-consuming user-unfriendly electronic forms into user-friendly formats, saving up to 50% of user time.
User friendly database validation software
A novel method of measuring the time course of degradation of perceptual sensitivity due to disease
A method of delivering chromium, copper, zinc, manganese, and selenium to cattle through transgenic algae.
Production of selenocysteine using transgenic algae to create industrial sized yields.
Innovative thermogenic biologicals, methods of delivery, and combinational therapy for the treatment of abdominal obesity
Identification and use of novel adipokines for reduction of visceral fat using thermogenesis.
A technique to increase the processing speed of data collection without losing accuracy
Addition of low concentration aliovalent transition metal dopants substantially improves particle performance in chemical loopiong systems
A model to predict CYP7A1 activity and individual response to statins.
Nasal sinusitis is one of the most common medical conditions in the US, affecting an estimated 12% of individuals, or some 29.4 million people (National Health Interview Survey 2015, CDC).Topical sinus irrigations (e.g. neti-pot, irrigation squeeze bottles) play an integral role in the management of sinusitis and are often more effective in drug delivery than other topical methods such as nasal sprays, nebulizers, or atomizers. However, due to the intricate anatomy of the human nasal airway, the ability to reach target sinuses is highly variable and unpredictable. While the irrigation procedure includes many variables, such as head position, injection angle, and flow rates, the optimal balance is unknown. Additionally, there are likely significant differences between individual sinuses that may change the optimal conditions. For this reason, when a patient's symptoms fail to improve after repeated irrigations, it is difficult to determine whether the irrigation itself is not working, or the irrigation doesn’t penetrate effectively.
Researchers at The Ohio State University led by Kai Zhao, have developed an irrigation guidance method based on 3D printed replicas of patients' nasal cavities. These replicas provide patients and clincians with the ability to view models for determining more precise, personalized irrigation strategies.
A new tool that can quantify the sensory maps of the human brain. The tool can be used to quantify plasticity and pathology in the sensory areas of the human brain that are associated with normal and abnormal development, aging, and diseases in sensory systems. The first application of the tool, on retinotopic maps of the visual cortex, has generated excellent results.
The implantation of engineered thermogenic cells for treating metabolic disease