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An improved delivery mechanism has been developed for camptothecin derivatives which will increase chemotherapeutic efficacy.
An efficient delivery vehicle for therapeutic oligonucleotides with high efficiency.
Nucleolin (NCL) is up-regulated in cancer cells, and modulates pro-tumorigenic pathways and chemoresistance. This anti-NCL agent binds and blocks NCL signaling, and may be optimized as cancer therapeutic and diagnostic tool.